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The Most Interesting Medical Cases in Hematology

Hematologists and other healthcare professionals regularly share new and fascinating cases to . Here are five of the most interesting medical cases in hematology causing buzz in the community.

#5.

This blood smear shows, according to 乐播传媒 members, 鈥渁 fantastic example鈥 of auer rods present in a patient diagnosed with acute promyelocytic leukemia (APL). 

#4.

The fourth most interesting hematology-related medical case shows a pseudo tumor in a patient with hemophilia. According to the 乐播传媒 member who shared the case, the patient did not receive regular factor therapy for their hemophilia, which caused 鈥渞epeated bleeding in the area鈥. Repeated bleeding in the muscle eventually led to bone issues and the patient鈥檚 leg was amputated.

#3.

A patient with Von Willebrand disease sustained this injury from a dirt biking accident. Several 乐播传媒 members warned that a reduction was needed immediately: 鈥淚 would reduce the fracture ASAP and apply light dressing and refer to a foot and ankle specialist for delayed repair of syndesmotic injury. During acute phase, watch out for compartment syndrome,鈥 a podiatrist offered. Another podiatrist cautioned, 鈥淐losed reduction in the ED may not even work, this is pretty unstable. If unsuccessful, needs to go to the OR to put on a delta frame.鈥

#2.

In this case, we see the clubbed fingers of a patient with sickle cell disease. One study deemed clubbed fingers part of the 鈥 that may indicate shortened survival in such patients”.

Several 乐播传媒 members commented that this was one of the most extreme examples of clubbed fingers they鈥檇 seen. 

#1.

In the most interesting hematology medical case, an internal medicine physician shared the case details of a 15-year-old patient with a longstanding history of anemia requiring several blood transfusions. The patient’s younger sibling also has anemia. Additional details included:

  • Jaundice
  • Dysmorphic features
  • Gray hair
  • Small palpebral fissure
  • Leukoplakia
  • Normal IQ and developmental milestones
  • Hepatosplenomegaly
  • Ectopic kidney
  • Normochromic normocytic with normal to high MCV
  • Hemoglobin electrophoresis with slightly raised fetal Hb
  • Negative Coomb鈥檚 test
  • Slightly raised retic count
  • Indirect hyperbilirubinemia
  • Normal liver enzymes

Several 乐播传媒 members chimed in with differentials, including Fanconi syndrome, Diamond-Blackfan anemia, hemolytic anemia, and sickle cell disease.

Published February 5, 2024


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